Ligandrol, which is also known by the development codes LGD-4033 and VK5211 and the name Anabolicum, was initially developed by the companyÂ Ligand PharmaceuticalsÂ in the United States. It wasÂ patented in 2009.
The results of the first human clinical trial were published in 2013, where takingÂ Ligandrol was found to increase muscle massÂ without also putting on fat.
The drug rights have since been licensed to the companyÂ Viking Therapeutics. In 2018, it completed a clinical trial which examinedÂ Ligandrol for people aged over 65 who were recovering from a hip fracture. The results showed patients who took Ligandrol significantly increased their muscle mass and could walk further than patients not on the drug.
The drug has also been examined forÂ other conditions, including as a possible treatment for cancer-related weight loss, enlarged prostates, for patients who have a diminished function of testes and ovaries, and as a potential cure for breast cancer.
Ligandrol is still considered an experimental drug, and as such, is not approved for sale by the Australian Therapeutic Goods Administration (TGA).
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